Bioflavonoids are comprised of many nutrients that have antioxidant activity. Citrus bioflavonoids come from the pulp and rind of citrus fruits. They have properties similar to vitamins and they work with vitamin C. Vitabase Citrus Bioflavonoids Complex also includes the important flavonoids hesperidin and rutin in order to help strengthen your circulatory system. Each tablet contains 1000 mg of this complex. As a dietary supplement, adults take one tablet, 1-3 times daily with meals, or as directed by a health care professional