Description 90 Tabs Tabs Size: S, Pill Size Guide Timed-Release Real-AKG from Swanson Ultra Arginine alpha-Ketoglutarate energy formula designed specifically for seniors Includes complementary nutrients to enhance uptake and improve results "This product packs a lot into such a little pill-- the supporting nutrients are all linked to assisting in arginine uptake. Combined with a timed release, it's a great pill in theory AND in practice." ~product review by Perko If you liked our Oxegen-AKG formula, you'll love new Real-AKG. Developed by the same skilled scientists at Innovation Labs, Real-AKG goes beyond simple Arginine AKG supplements by including complementary nutrients to enhance uptake and improve results. The Real-AKG formula includes a proprietary L-Citrulline extract from watermelon, vitamin C from Pureway-C and a blend of grape skin and grape seed extracts. Real-AKG delivers stimulant-free energizing support perfect for seniors seeking to improve daily energy without unwanted side-effects. Product Label: Timed-Release Real-AKG Arginine Alpha-Ketoglutarate Supplement Facts Serving Size 1 Tablet Amount Per Serving % Daily Value Vitamin C USP (from PureWay-C® ascorbic acid) 120 mg 200% Real-AKG™ (arginine alpha-ketoglutarate) 1 gram * PureWay-C® [proprietary formulation of ascorbic acid USP combined with lipid metabolites (fatty acids) from vegetable waxes] 134 mg * Watermelon Fruit Extract (Citrulius lanatus) (as Matraxol Amino™ proprietary formula of L-citrulline and lipid metabolites) 100 mg * Grape Skin Extract (Vitis vinifera) [providing a minimum 31% total polyphenols (20 mg)] 65 mg * Grapeseed Extract (Vitis vinifera) (standardized to 95% proanthocyanidins) 50 mg * *Daily Value not established. Other ingredients: Stearic acid, croscarmellose sodium, pharmaceutical glaze, may contain one or more of the following: microcrystalline cellulose (plant fiber), magnesium stearate, silica. Suggested Use: As a dietary supplement, take one tablet three times per day on an empty stomach with water. WARNING: Not intended for use by children or pregnant or nursing women. Consult your healthcare provider before use if you are taking any prescription medication or if you have renal or liver disease. Reduce dosage if you experience nausea, abdominal cramps or diarrhea. Matraxol Amino™, PureWay-C® and Real-AKG Matraxol Technology® are trademarks of Innovation Laboratories, Inc. and are used here under license. U.S. and international patents pending. Alpha-ketoglutaric acid is a substance found naturally in the human body. Also available in dietary supplement form, alpha-ketoglutaric acid plays a key role in the Krebs cycle (a series of chemical reactions involved in the body's production of energy). Alpha-ketoglutaric acid supplements are purported to offer a variety of health benefits. Alpha-ketoglutaric acid also occurs in salt form, as a substance called alpha-ketoglutarate. Alpha-ketoglutarate is involved in the formation of glutamine, an amino acid required for protein synthesis and for proper functioning of the immune system. Uses for Alpha-Ketoglutaric Acid Alpha-ketoglutaric acid is often said to enhance athletic performance. Some alternative medicine proponents claim that use of alpha-ketoglutaric acid can help stimulate the body's production of protein, stabilize blood sugar levels during exercise, and improve exercise endurance. In alternative medicine, alpha-ketoglutaric acid is also said to help with the following health problems: bacterial infections cataracts kidney disease yeast infections Health Benefits of Alpha-Ketoglutaric Acid Although research on the health effects of alpha-ketoglutaric acid is very limited, some preliminary research suggests that alpha-ketoglutarate may offer certain health benefits. Here's a look at several key findings from the available studies: 1) Hemodialysis Alpha-ketoglutarate may be of some benefit to people undergoing hemodialysis. In a study published in the journal Nephron in 1996, researchers found that administering a combination of alpha-ketoglutarate and calcium carbonate to hemodialysis patients helped boost amino acid metabolism and decrease hyperphosphatemia (a condition marked by abnormally elevated levels of phosphate in the blood). 2) Cardiac Surgery Alpha-ketoglutarate may help improve kidney function among patients undergoing cardiac surgery, according to a 1998 study from the Annals of Thoracic Surgery. The study involved 22 people with normal kidney function prior to undergoing cardiac surgery. Of those patients, 11 people received an intravenous infusion of alpha-ketoglutarate an hour after their surgery. Study results suggest that alpha-ketoglutarate may enhance blood flow in the kidneys. 3) Longevity A 2014 study published in Nature suggests that alpha-ketoglutarate may show promise in increasing longevity. In tests on the nematode worm Caenorhabditis elegans, the study's authors determined that alpha-ketoglutarate interfered with cellular energy production and mimicked the effects of diets very low in calories, which have been shown to extend the lifespan of certain animals. According to the study's authors, alpha-ketoglutarate boosted the lifespan of the treated worms by approximately 50% over untreated controls. Further study is needed to see what effects the compound would have in humans. Caveats Due to a lack of research, little is known about the safety of long-term or regular use of supplements containing alpha-ketoglutaric acid. However, there's some concern that consumption of alpha-ketoglutaric acid may irritate the esophagus and/or upset the stomach. It's important to keep in mind that supplements haven't been tested for safety and dietary supplements are largely unregulated. In some cases, the product may deliver doses that differ from the specified amount for each herb. In other cases, the product may be contaminated with other substances such as metals. Also, the safety of supplements in pregnant women, nursing mothers, children, and those with medical conditions or who are taking medications has not been established. You can get further tips on using supplements here. Alternatives to Alpha-Ketoglutaric Acid A number of other natural remedies may be of some use in improving athletic performance. For instance, some research indicates that branched-chain amino acids may help improve physical performance and prevent fatigue during long periods of exercise. In addition, phosphatidylserine supplements have been found to boost exercise capacity, as well as decrease muscle soreness and protect against the increase in levels of cortisol (a hormone released during stress) that often results from overtraining. There's also some evidence that creatine may boost performance in high-intensity, short-duration activities (such as weight-lifting and sprinting).

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