Cascara sagrada provides gentle overnight support for regular bowel movements. Vitabase Cascara Sagrada is aged for one year to optimize the active constituents. Each capsule contains 450 mg of cascara sagrada. As a dietary supplement, adults take one (1) capsule with eight (8) oz. water at bedtime, or as directed by a health care professional. Use with caution if pregnant or lactating. Store in a cool, dry place and away from direct light.